88 Ways to Screen a Chiral Compound - September 2017
The bottle neck in a busy purification laboratory quite often is not the purification itself, but finding the right method. Chiral screening used to mean lots of waiting and probably (at Reach, definitely!) lots of coffee, as each column was equilibrated and each method ran. It could easily take 30-.....
Developing an achiral SFC screen - 8th February 2016
Here at Reach Separations we are not ones to shy away from promoting the benefits of SFC. Both the time and energy savings during post processing and evaporation, and the reduction in organic solvents used, make SFC a greener technique than traditional normal phase methods.
However, we admit that w.....
Coming to the end of my Placement - July 2015
I am coming to the end of my 12 month industrial placement at Reach Separations, and I wanted to share some of my reflections on how the year has progressed. Earlier in my placement, I wrote a piece about why I chose to work at Reach and beginning my project. I definitely pushed myself out of my com.....
Optimising Manufacturer Injection Protocol - 21th November 2014
A recent addition to the laboratory here at Reach Separations is an Aurora Fusion SFC. Another analytical system that we hope to put into use to speed up screening, both for chiral and achiral separations. However, not being ones to accept straight off the shelf equipment, or out of the manual metho.....
A day in the life of a chiral sample. - 12th September 2014
A day in the life of a chiral sample - 12th September 2014
In any given week Reach Separations can get up to 20 samples entering the lab. The life of a sample here at Reach is a short but interesting one. This is the story of a standard sample for chiral purification as it passes through one of ou.....
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