REACH SEPARATIONS

PROTACs & Molecular Glue Purification

Your trusted partner for
Beyond-Rule-of-5, PROTACs & Molecular Glue purification.

Precision in PROTACs & Molecular Glue Purification

With our extensive expertise in analysing and purifying complex molecules with diverse physicochemical properties, we are your trusted partner for bRo5 purification. Our automated and bespoke screening processes identify the optimal method for your specific compound. Leveraging an industry-leading array of column chemistries and cutting-edge instrumentation across both LC and SFC, we are equipped to tackle even the most challenging molecules.

Our PROTACs & Molecular Glue Purification Services 

Reach Separations offers specialised purification services for PROTACs and molecular glues, including: 

  • Supercritical Fluid Chromatography (SFC): A highly efficient technique for purifying complex PROTACs and molecular glues, providing excellent resolution and orthogonal selectivity.
  • Reverse Phase HPLC: Perfect for separating a variety of components, our reverse phase HPLC systems offer high-resolution purification, delivering optimal purity.
  • Experimental Polar Surface Area (EPSA): We offer the option to run EPSA on all purified bRo5 compounds. Discover more about our EPSA services here.

Why Choose Reach Separations?

  • High Purity Levels: We specialise in achieving up to 99% purity for PROTACs and molecular glues, ensuring that these cutting-edge compounds meet the most stringent industry standards with our advanced purification techniques and a deep understanding of the unique challenges posed by these complex molecules.
  • Advanced Technology: We enhance the quality of your PROTACs and molecular glues with precision and efficiency, utilising our extensive array of SFC and Reverse Phase HPLC systems. Our advanced technology allows us to achieve optimal separation and purification.
  • Customised Solutions: We offer tailored purification solutions designed to meet the unique needs of your projects. From early development to large-scale production, we customise our processes to ensure optimal purification at every phase.
  • Trusted Partner: We deliver reliable solutions that enhance the success of your compounds. Our dedication to meticulous process control and quality assurance means you can move forward with full confidence in the readiness and integrity of your therapeutic assets.

Partner with Reach Separations 

For unmatched precision and purity in bRo5, PROTAC, and molecular glue purification, partner with Reach Separations. Our expert team is dedicated to delivering the highest quality results, customised to your project’s needs.